SAA2

Across TCGA patient cohorts, SAA2 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SAA2-associated genes across cancer lineages are RNU1-48P, RN7SKP145, and RNU6-1097P. Each is linked with SAA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA2-to-partner and partner-to-SAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-48P grouped by SAA2-low versus SAA2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA2→partner) and Y-score (partner→SAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-48P →	+0.179	+7.640	<.001	.009	3	2
LUAD	RN7SKP145 →	+0.099	+7.930	<.001	.008	3	1
LUAD	RNU6-1097P →	+0.253	+7.930	<.001	.008	3	1
LUAD	TRAPPC2P3 →	+0.094	+7.930	<.001	.008	3	1
UCEC	MIR6090 →	+0.768	+5.358	<.001	.006	3	1
UCEC	MIR107 →	+0.595	+5.358	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

RNU1-48P by SAA2 expression — BLCA

Explore this box plot interactively →