SAA2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SAA2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LGG shows the largest number of these associations.

The most reproducible SAA2-associated genes across cancer lineages are CD4+ naive T-cells. Each is linked with SAA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA2-to-partner and partner-to-SAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ naive T-cells grouped by SAA2-low versus SAA2-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA2→partner) and Y-score (partner→SAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LGGCD4+ naive T-cells →+0.012+7.389<.001.01131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ naive T-cells by SAA2 expression — LGG

Box plot of CD4+ naive T-cells in SAA2-low vs SAA2-high samples in LGG.

Explore this box plot interactively →

Exploration