SAA2

Across TCGA cell cohorts, SAA2 mutation is significantly associated with the mutation status of many other genes, with 255 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAA2-associated genes across cancer lineages are WDR37, ZNF821, and CCDC113. Each is linked with SAA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA2-to-partner and partner-to-SAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR37 grouped by SAA2-low versus SAA2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA2→partner) and Y-score (partner→SAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	WDR37 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	ZNF821 →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	CCDC113 →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	TAF5 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SREK1IP1 →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	UBXN10 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 255 associations by consensus.

WDR37 by SAA2 expression — LARGE_INTESTINE

Explore this box plot interactively →