S1PR5

Across TCGA patient cohorts, S1PR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,216 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S1PR5-associated proteins across cancer lineages are MCAM, NID2, and SEC13. Each is linked with S1PR5 in more than 4 cancer types. Because this analysis shows association rather than direction, both S1PR5-to-partner and partner-to-S1PR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S1PR5 versus MCAM in BRCA, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR5→partner) and Y-score (partner→S1PR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MCAM →	+0.548	+0.491	<.001	.002	3	5
UCEC	NID2 →	+0.626	+0.365	.003	.005	3	5
GBM	SEC13 →	-0.202	-1.264	<.001	<.001	3	5
CCRCC	SEC24A →	-0.264	-0.637	<.001	<.001	3	5
CCRCC	CDH13 →	+0.637	+0.770	<.001	<.001	3	5
OV	LAMA4 →	+0.909	+0.482	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,216 associations by consensus.

S1PR5 vs MCAM — BRCA

Explore this scatter interactively →