S1PR5

Across TCGA patient cohorts, S1PR5 protein abundance is significantly associated with the RNA expression of many other genes, with 553 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S1PR5-associated genes across cancer lineages are TPTEP1, CSTF2, and MSLN. Each is linked with S1PR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both S1PR5-to-partner and partner-to-S1PR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S1PR5 versus TPTEP1 in GBM, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR5→partner) and Y-score (partner→S1PR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPTEP1 →	+0.857	+0.732	.003	.002	3	1
GBM	CSTF2 →	-0.311	-0.603	.005	.008	3	1
GBM	MSLN →	+0.930	+0.832	.004	.002	3	1
GBM	USP31 →	+0.312	+0.572	.007	<.001	3	1
GBM	ASF1B →	-0.784	-0.672	.006	.003	3	1
GBM	APLP1 →	+1.181	+0.778	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 553 associations by consensus.

S1PR5 vs TPTEP1 — GBM

Explore this scatter interactively →