S1PR5

Across TCGA cell cohorts, S1PR5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,667 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible S1PR5-associated genes across cancer lineages are CHRAC1, EXOSC2, and BAZ1A. Each is linked with S1PR5 in more than 9 cancer types. Because this analysis shows association rather than direction, both S1PR5-to-partner and partner-to-S1PR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S1PR5 versus CHRAC1 in CNS, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR5→partner) and Y-score (partner→S1PR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CHRAC1 →	+0.644	+0.899	.003	.004	2	10
BREAST	EXOSC2 →	+0.940	+0.812	<.001	<.001	3	9
OESOPHAGUS	BAZ1A →	+1.372	+1.153	<.001	.002	3	8
PANCREAS	NUP188 →	+1.272	+1.011	<.001	.004	3	8
PANCREAS	RUVBL1 →	+0.884	+1.204	<.001	<.001	3	7
CNS	EXOSC4 →	+0.772	+0.786	.002	.007	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,667 associations by consensus.

S1PR5 vs CHRAC1 — CNS

Explore this scatter interactively →