Across TCGA patient cohorts, S1PR3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,461 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S1PR3-associated genes across cancer lineages are EEF1B2P6, ZNF165, and ARL5AP5. Each is linked with S1PR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both S1PR3-to-partner and partner-to-S1PR3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR3→partner) and Y-score (partner→S1PR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EEF1B2P6 →	+1.139	+0.333	.008	.007	3	2
BRCA	ZNF165 →	+0.878	+0.326	<.001	.009	3	2
BRCA	ARL5AP5 →	+0.938	+0.559	.001	<.001	3	2
BRCA	XRCC6P2 →	+1.680	+0.585	.004	.001	3	2
GBM	RNA5SP464 →	-0.603	-0.450	<.001	<.001	3	2
LSCC	FGF9 →	+0.259	+0.699	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

Exploration

S1PR3 survival (RNA) · tumor vs normal (RNA) · all S1PR3 data types