S100PBP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, S100PBP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated S100PBP data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher S100PBP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated S100PBP expression acts as an unfavorable survival marker.

LUAD, UCEC, and SKCM are the cancer types where S100PBP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianII,III,IV0.3260.753.01327view →
UCECOSMedianIV0.2310.592.0366view →
SKCMOSMedianAll0.1130.323.0442view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

S100PBP–LUAD (OS)

Kaplan–Meier survival curve for S100PBP mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration