S100PBP

Across TCGA pan-cancer cohorts, S100PBP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated S100PBP data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher S100PBP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated S100PBP expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where S100PBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.218	0.645	.010	24	view →
LUAD	DFS	Tertile	All	0.985	0.821	.009	19	view →
HNSC	DFS	Quartile	All	0.442	0.919	.016	8	view →
LSCC	OS	Tertile	All	0.970	0.766	.008	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

S100PBP–PDAC (OS)

Open the PDAC breakdown →