S100PBP

Across TCGA patient cohorts, S100PBP protein abundance is significantly associated with the RNA expression of many other genes, with 4,713 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S100PBP-associated genes across cancer lineages are AKR1E2, SEPTIN7P9, and AKR1C2. Each is linked with S100PBP in more than 2 cancer types. Because this analysis shows association rather than direction, both S100PBP-to-partner and partner-to-S100PBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100PBP versus AKR1E2 in UCEC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100PBP→partner) and Y-score (partner→S100PBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKR1E2 →	-1.363	-0.309	.004	<.001	3	3
HNSC	SEPTIN7P9 →	+1.180	+0.608	.005	<.001	3	3
UCEC	AKR1C2 →	-2.267	-0.352	.003	<.001	3	2
BRCA	EML2 →	-0.508	-0.346	.005	<.001	3	2
GBM	PKP4 →	-0.582	-0.316	<.001	<.001	3	2
PDAC	LACTB2 →	-0.785	-0.512	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,713 associations by consensus.

S100PBP vs AKR1E2 — UCEC

Explore this scatter interactively →