S100PBP

Across TCGA patient cohorts, S100PBP mutation is significantly associated with the RNA expression of many other genes, with 2,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100PBP-associated genes across cancer lineages are MIR4698, MIR3926-1, and RNA5SP419. Each is linked with S100PBP in more than 1 cancer types. Because this analysis shows association rather than direction, both S100PBP-to-partner and partner-to-S100PBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4698 grouped by S100PBP-low versus S100PBP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100PBP→partner) and Y-score (partner→S100PBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4698 →	+0.291	+2.894	.001	.001	3	2
UCEC	MIR3926-1 →	+0.354	+2.247	.001	.008	3	2
UCEC	RNA5SP419 →	+0.797	+2.714	<.001	<.001	3	2
UCEC	RNA5SP415 →	+0.540	+2.351	<.001	.006	3	2
SKCM	RNU6-660P →	+0.648	+4.884	<.001	.004	3	2
STAD	CYCSP26 →	+0.380	+3.828	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,937 associations by consensus.

MIR4698 by S100PBP expression — UCEC

Explore this box plot interactively →