S100PBP

Across TCGA cell cohorts, S100PBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible S100PBP-associated GO terms across cancer lineages are DNA biosynthetic process, Positive regulation of organelle assembly, and Spliceosomal complex assembly. Each is linked with S100PBP in more than 18 cancer types. Because this analysis shows association rather than direction, both S100PBP-to-partner and partner-to-S100PBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA biosynthetic process grouped by S100PBP-low versus S100PBP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100PBP→partner) and Y-score (partner→S100PBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DNA biosynthetic process →	+0.075	+0.947	.001	.004	3	19
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.076	+1.084	<.001	.001	3	19
STOMACH	Spliceosomal complex assembly →	+0.094	+0.892	.005	<.001	3	18
BREAST	Regulation of cytokinesis →	+0.081	+0.818	.001	.001	3	18
BONE	Protein-DNA complex organization →	+0.097	+0.828	<.001	<.001	3	18
STOMACH	Heterochromatin formation →	+0.075	+0.970	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,595 associations by consensus.

DNA biosynthetic process by S100PBP expression — LUNG_NSCLC_LUSC

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