S100A9

Across TCGA cell cohorts, S100A9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,912 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible S100A9-associated GO terms across cancer lineages are Protein nitrosylation, Peptidyl-cysteine S-nitrosylation, and NMDA selective glutamate receptor signaling pathway. Each is linked with S100A9 in more than 10 cancer types. Because this analysis shows association rather than direction, both S100A9-to-partner and partner-to-S100A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein nitrosylation grouped by S100A9-low versus S100A9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A9→partner) and Y-score (partner→S100A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein nitrosylation →	-0.248	-2.700	<.001	.001	3	11
OVARY	Peptidyl-cysteine S-nitrosylation →	-0.248	-2.700	<.001	.001	3	11
LUNG_NSCLC_LUSC	NMDA selective glutamate receptor signaling pathway →	+0.266	+4.322	<.001	<.001	3	10
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.135	+5.047	<.001	<.001	3	10
URINARY_TRACT	Response to indole-3-methanol →	+0.165	+4.781	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Complement activation, lectin pathway →	+1.196	+3.784	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

Protein nitrosylation by S100A9 expression — OVARY

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