Across TCGA patient cohorts, S100A6 RNA expression is significantly associated with the RNA expression of many other genes, with 17,809 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible S100A6-associated genes across cancer lineages are S100A4, S100A11, and LGALS3. Each is linked with S100A6 in more than 32 cancer types. Because this analysis shows association rather than direction, both S100A6-to-partner and partner-to-S100A6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A6→partner) and Y-score (partner→S100A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	S100A4 →	+2.724	+1.421	<.001	<.001	3	33
LIHC	S100A11 →	+2.010	+2.301	<.001	<.001	3	31
LAML	LGALS3 →	+2.390	+1.829	<.001	<.001	3	30
BLCA	S100A5 →	+1.661	+1.405	<.001	<.001	3	30
LAML	LMNA →	+1.903	+1.430	<.001	<.001	3	30
THYM	CD63 →	+0.802	+1.204	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,809 associations by consensus.

Exploration

S100A6 survival (RNA) · tumor vs normal (RNA) · all S100A6 data types