Across TCGA patient cohorts, S100A6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,108 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S100A6-associated proteins across cancer lineages are S100A16, ANXA2, and S100A11. Each is linked with S100A6 in more than 7 cancer types. Because this analysis shows association rather than direction, both S100A6-to-partner and partner-to-S100A6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A6→partner) and Y-score (partner→S100A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	S100A16 →	+0.679	+1.285	<.001	<.001	3	8
OV	ANXA2 →	+0.590	+1.440	<.001	<.001	3	7
GBM	S100A11 →	+0.519	+0.593	<.001	<.001	3	6
UCEC	SERPINB1 →	+0.520	+2.132	<.001	<.001	3	6
LSCC	LAMB3 →	+0.798	+0.733	.001	.002	3	6
UCEC	LAMC2 →	+0.753	+1.688	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,108 associations by consensus.

Exploration

S100A6 survival (RNA) · tumor vs normal (RNA) · all S100A6 data types