Across TCGA patient cohorts, S100A6 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100A6-associated genes across cancer lineages are MIR7702, LCE1E, and MIR425. Each is linked with S100A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A6-to-partner and partner-to-S100A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A6→partner) and Y-score (partner→S100A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.949	+7.060	<.001	<.001	3	1
UCEC	LCE1E →	+0.168	+4.423	<.001	.006	3	1
UCEC	MIR425 →	+0.990	+4.499	<.001	.005	3	1
UCEC	RNU6-271P →	+0.547	+4.852	<.001	.006	3	1
UCEC	RNU6-1082P →	+0.635	+4.551	<.001	.009	3	1
UCEC	TRGJP2 →	+1.064	+4.473	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

S100A6 survival (RNA) · tumor vs normal (RNA) · all S100A6 data types