Across TCGA cell cohorts, S100A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,163 significant associations in total. BONE shows the largest number of these associations.

The most reproducible S100A6-associated GO terms across cancer lineages are Negative regulation of alpha-beta T cell activation, 'de novo' IMP biosynthetic process, and Macrophage colony-stimulating factor signaling pathway. Each is linked with S100A6 in more than 12 cancer types. Because this analysis shows association rather than direction, both S100A6-to-partner and partner-to-S100A6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A6→partner) and Y-score (partner→S100A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of alpha-beta T cell activation →	+0.092	+3.908	<.001	<.001	3	13
OVARY	'de novo' IMP biosynthetic process →	-0.135	-4.701	<.001	<.001	3	13
BONE	Macrophage colony-stimulating factor signaling pathway →	+0.982	+4.069	<.001	<.001	3	12
LIVER	Urokinase plasminogen activator signaling pathway →	+1.525	+4.897	<.001	<.001	3	12
OESOPHAGUS	Striated muscle atrophy →	+0.271	+1.722	<.001	.003	3	12
LIVER	Negative regulation of muscle adaptation →	+0.249	+4.101	.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,163 associations by consensus.

Exploration

S100A6 survival (RNA) · tumor vs normal (RNA) · all S100A6 data types