Across TCGA cell cohorts, S100A6 protein abundance is significantly associated with the RNA expression of many other genes, with 6,333 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible S100A6-associated genes across cancer lineages are RPL3, IMPDH2, and IMP4. Each is linked with S100A6 in more than 5 cancer types. Because this analysis shows association rather than direction, both S100A6-to-partner and partner-to-S100A6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A6→partner) and Y-score (partner→S100A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RPL3 →	+0.719	+0.758	<.001	.001	3	6
LUNG_SCLC	IMPDH2 →	+0.942	+0.745	.001	.003	3	6
OVARY	IMP4 →	+1.098	+1.371	<.001	<.001	3	6
OVARY	NOB1 →	+0.887	+1.090	.002	.001	3	6
BREAST	BAG2 →	+1.931	+0.899	<.001	.001	3	6
LARGE_INTESTINE	TOMM22 →	+0.805	+0.849	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,333 associations by consensus.

Exploration

S100A6 survival (RNA) · tumor vs normal (RNA) · all S100A6 data types