Across TCGA patient cohorts, S100A5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,695 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible S100A5-associated proteins across cancer lineages are S100A6, SSRP1, and ACAP2_S521. Each is linked with S100A5 in more than 5 cancer types. Because this analysis shows association rather than direction, both S100A5-to-partner and partner-to-S100A5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A5→partner) and Y-score (partner→S100A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	S100A6 →	+1.220	+1.638	<.001	<.001	3	6
HNSC	SSRP1 →	+0.420	+1.055	<.001	.001	3	5
LSCC	ACAP2_S521 →	+0.498	+0.625	<.001	<.001	3	4
LSCC	NOM1 →	+0.406	+0.872	.001	<.001	3	4
HNSC	HNRNPLL →	+0.333	+1.334	<.001	<.001	3	4
HNSC	C1orf35 →	+0.414	+0.836	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,695 associations by consensus.

Exploration

S100A5 survival (RNA) · tumor vs normal (RNA) · all S100A5 data types