Across TCGA patient cohorts, S100A5 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100A5-associated genes across cancer lineages are RNA5SP222, RN7SL601P, and RN7SL565P. Each is linked with S100A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A5-to-partner and partner-to-S100A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A5→partner) and Y-score (partner→S100A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP222 →	+0.453	+4.069	<.001	.008	3	2
SKCM	RN7SL601P →	+0.249	+7.816	<.001	.008	3	1
BLCA	RN7SL565P →	+0.083	+7.640	<.001	.009	3	1
BLCA	MIR8074 →	+0.339	+7.640	<.001	.009	3	1
COAD	IGHVII-44-2 →	+0.214	+7.741	<.001	.009	3	1
LUAD	LRRC30 →	+0.034	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

S100A5 survival (RNA) · tumor vs normal (RNA) · all S100A5 data types