Across TCGA cell cohorts, S100A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,541 significant associations in total. BONE shows the largest number of these associations.

The most reproducible S100A5-associated GO terms across cancer lineages are Barbed-end actin filament capping, Urokinase plasminogen activator signaling pathway, and Bleb assembly. Each is linked with S100A5 in more than 7 cancer types. Because this analysis shows association rather than direction, both S100A5-to-partner and partner-to-S100A5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A5→partner) and Y-score (partner→S100A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Barbed-end actin filament capping →	+0.217	+0.465	<.001	<.001	3	8
BREAST	Urokinase plasminogen activator signaling pathway →	+1.078	+0.940	.001	.007	3	7
BONE	Bleb assembly →	+0.228	+0.409	<.001	<.001	3	7
BONE	Actin filament capping →	+0.182	+0.455	<.001	<.001	3	7
BONE	Maintenance of protein localization in organelle →	+0.100	+0.438	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Negative regulation of muscle adaptation →	+0.246	+0.735	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,541 associations by consensus.

Exploration

S100A5 survival (RNA) · tumor vs normal (RNA) · all S100A5 data types