Across TCGA cell cohorts, S100A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,478 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible S100A4-associated GO terms across cancer lineages are Positive chemotaxis, Response to bacterial lipoprotein, and Fatty acid metabolic process. Each is linked with S100A4 in more than 10 cancer types. Because this analysis shows association rather than direction, both S100A4-to-partner and partner-to-S100A4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A4→partner) and Y-score (partner→S100A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive chemotaxis →	+0.148	+3.525	<.001	.003	3	11
BLOOD_Leukemia	Response to bacterial lipoprotein →	+0.888	+2.230	<.001	.005	3	8
OESOPHAGUS	Fatty acid metabolic process →	+0.049	+3.319	.001	<.001	3	8
SOFT_TISSUE	Monocarboxylic acid transport →	+0.046	+2.941	<.001	<.001	3	7
BLOOD_Leukemia	Negative regulation of cell motility →	+0.038	+2.705	<.001	<.001	3	7
SKIN	Long-term synaptic potentiation →	+0.084	+4.287	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,478 associations by consensus.

Exploration

S100A4 survival (RNA) · tumor vs normal (RNA) · all S100A4 data types