Across TCGA patient cohorts, S100A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,169 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible S100A3-associated proteins across cancer lineages are S100A2, CSPG4, and S100A4. Each is linked with S100A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both S100A3-to-partner and partner-to-S100A3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A3→partner) and Y-score (partner→S100A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	S100A2 →	+2.361	+0.818	<.001	<.001	3	7
BRCA	CSPG4 →	+0.614	+0.828	<.001	.002	3	7
BRCA	S100A4 →	+0.889	+1.065	<.001	<.001	3	6
PDAC	JUNB →	+0.396	+0.860	<.001	<.001	3	6
BRCA	MMP14 →	+0.628	+0.895	<.001	<.001	3	6
LSCC	AHNAK2 →	+0.895	+0.868	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,169 associations by consensus.

Exploration

S100A3 survival (RNA) · tumor vs normal (RNA) · all S100A3 data types