Across TCGA patient cohorts, S100A3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,104 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible S100A3-associated genes across cancer lineages are HMCN1, CNRIP1, and CASS4. Each is linked with S100A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both S100A3-to-partner and partner-to-S100A3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A3→partner) and Y-score (partner→S100A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMCN1 →	+0.935	+1.596	.001	<.001	3	4
BRCA	CNRIP1 →	+0.700	+0.426	<.001	<.001	3	4
LUAD	CASS4 →	+0.571	+0.480	<.001	<.001	3	4
OV	GEM →	+1.370	+1.126	.009	.008	3	3
BRCA	LNCAROD →	+0.732	+0.600	.005	.001	3	3
UCEC	ANOS1 →	+0.885	+1.377	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,104 associations by consensus.

Exploration

S100A3 survival (RNA) · tumor vs normal (RNA) · all S100A3 data types