Across TCGA cell cohorts, S100A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,432 significant associations in total. BONE shows the largest number of these associations.

The most reproducible S100A3-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Collagen fibril organization, and Regulation of plasma membrane repair. Each is linked with S100A3 in more than 13 cancer types. Because this analysis shows association rather than direction, both S100A3-to-partner and partner-to-S100A3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A3→partner) and Y-score (partner→S100A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Establishment of epithelial cell apical/basal polarity →	+0.207	+2.110	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.370	+2.075	.001	.002	2	13
BONE	Regulation of plasma membrane repair →	+0.319	+2.013	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Extracellular structure organization →	+0.167	+1.842	.005	.005	2	12
LUNG_NSCLC_LUSC	External encapsulating structure organization →	+0.166	+1.842	.005	.005	2	12
LIVER	Pyrimidine-containing compound transmembrane transport →	-0.238	-3.463	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,432 associations by consensus.

Exploration

S100A3 survival (RNA) · tumor vs normal (RNA) · all S100A3 data types