Across TCGA patient cohorts, S100A2 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible S100A2-associated genes across cancer lineages are WBP1LP3, RN7SL87P, and RPL21P103. Each is linked with S100A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A2-to-partner and partner-to-S100A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A2→partner) and Y-score (partner→S100A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WBP1LP3 →	+0.144	+7.954	<.001	.008	3	1
SKCM	RN7SL87P →	+0.270	+5.212	<.001	.002	3	1
SKCM	RPL21P103 →	+0.228	+4.915	<.001	<.001	3	1
SKCM	RNU6-202P →	+0.343	+5.212	<.001	.002	3	1
SKCM	MIR4299 →	+0.354	+6.225	<.001	<.001	3	1
LUSC	CSPG4P4Y →	+0.018	+4.548	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

S100A2 survival (RNA) · tumor vs normal (RNA) · all S100A2 data types