Across TCGA patient cohorts, S100A16 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,729 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S100A16-associated proteins across cancer lineages are S100A16_S103, S100A14, and JUNB. Each is linked with S100A16 in more than 8 cancer types. Because this analysis shows association rather than direction, both S100A16-to-partner and partner-to-S100A16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A16→partner) and Y-score (partner→S100A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	S100A16_S103 →	+1.180	+1.192	<.001	<.001	3	9
LSCC	S100A14 →	+1.624	+1.247	<.001	<.001	3	8
GBM	JUNB →	+0.401	+0.989	.001	<.001	3	7
GBM	TPI1_S80 →	+0.537	+1.024	<.001	<.001	3	6
LSCC	LAMB3 →	+0.746	+1.030	<.001	<.001	3	6
LSCC	LAMC2 →	+0.900	+0.775	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,729 associations by consensus.

Exploration

S100A16 survival (RNA) · tumor vs normal (RNA) · all S100A16 data types