Across TCGA patient cohorts, S100A16 protein abundance is significantly associated with the RNA expression of many other genes, with 13,955 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A16-associated genes across cancer lineages are S100A13, S100A14, and S100A6. Each is linked with S100A16 in more than 8 cancer types. Because this analysis shows association rather than direction, both S100A16-to-partner and partner-to-S100A16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A16→partner) and Y-score (partner→S100A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S100A13 →	+1.025	+0.645	<.001	<.001	3	9
LSCC	S100A14 →	+2.381	+0.934	<.001	<.001	3	8
OV	S100A6 →	+1.285	+0.679	<.001	<.001	3	8
LSCC	KRT16 →	+2.674	+0.781	<.001	<.001	3	6
GBM	S100A10 →	+1.236	+0.592	<.001	<.001	3	6
UCEC	SERPINB1 →	+0.924	+0.622	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,955 associations by consensus.

Exploration

S100A16 survival (RNA) · tumor vs normal (RNA) · all S100A16 data types