Across TCGA patient cohorts, S100A16 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible S100A16-associated genes across cancer lineages are RNU6-839P, OOSP1P1, and RN7SL79P. Each is linked with S100A16 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A16-to-partner and partner-to-S100A16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A16→partner) and Y-score (partner→S100A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-839P →	+0.313	+7.640	<.001	.009	3	2
SKCM	OOSP1P1 →	+0.161	+4.680	<.001	.007	3	1
SKCM	RN7SL79P →	+0.252	+4.913	<.001	.002	3	1
SKCM	RN7SL497P →	+0.271	+5.034	<.001	.002	3	1
SKCM	LINC02283 →	+0.115	+5.469	.002	.002	3	1
SKCM	SRIP1 →	+0.163	+5.080	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

S100A16 survival (RNA) · tumor vs normal (RNA) · all S100A16 data types