S100A11P5

Across TCGA pan-cancer cohorts, S100A11P5 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated S100A11P5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher S100A11P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated S100A11P5 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

UVM, KIRC, and KICH are the cancer types where S100A11P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.381	0.688	<.001	104	view →
KIRC	OS	Tertile	II,III,IV	0.217	0.572	<.001	96	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUAD	DFS	Tertile	All	0.644	0.828	.008	57	view →
BRCA	DFS	Tertile	II,III,IV	0.480	0.529	.007	45	view →
LIHC	DFS	Tertile	All	0.268	0.565	.001	30	view →
ACC	OS	Tertile	All	0.700	0.888	.004	27	view →
BLCA	DFS	Tertile	All	0.435	0.296	.021	25	view →
COAD	DFS	Tertile	All	0.154	0.573	.004	18	view →
OV	OS	Tertile	IV	0.944	0.572	.032	18	view →
KIRP	DFS	Tertile	II,III,IV	0.428	0.775	.040	18	view →
READ	OS	Tertile	All	0.285	0.685	.029	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

S100A11P5–UVM (DFS)

Open the UVM breakdown →