Across TCGA cell cohorts, RYR3 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,115 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RYR3-associated GO terms across cancer lineages are Negative regulation of bone mineralization involved in bone maturation, Spleen development, and Phenol-containing compound metabolic process. Each is linked with RYR3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RYR3-to-partner and partner-to-RYR3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RYR3→partner) and Y-score (partner→RYR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of bone mineralization involved in bone maturation →	+0.941	+0.658	.001	.001	3	4
LUNG_SCLC	Spleen development →	+0.234	+1.692	.001	<.001	3	4
BLOOD_Leukemia	Phenol-containing compound metabolic process →	+0.077	+0.607	.001	<.001	3	3
BLOOD_Leukemia	Regulation of chaperone-mediated autophagy →	+0.139	+0.793	.001	.002	3	3
BLOOD_Leukemia	T cell proliferation involved in immune response →	+0.787	+0.724	<.001	.001	3	3
BLOOD_Leukemia	Negative regulation of interleukin-6 production →	+0.051	+0.725	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,115 associations by consensus.

Exploration

RYR3 survival (RNA) · tumor vs normal (RNA) · all RYR3 data types