RYBP

Across TCGA patient cohorts, RYBP protein abundance is significantly associated with the RNA expression of many other genes, with 4,178 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RYBP-associated genes across cancer lineages are VRK1, LINC01232, and MTMR3. Each is linked with RYBP in more than 2 cancer types. Because this analysis shows association rather than direction, both RYBP-to-partner and partner-to-RYBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RYBP versus VRK1 in LUAD, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RYBP→partner) and Y-score (partner→RYBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	VRK1 →	+0.512	+0.208	<.001	.002	3	3
LSCC	LINC01232 →	-0.682	-0.329	<.001	<.001	3	3
LSCC	MTMR3 →	-0.258	-0.209	<.001	<.001	3	2
LUAD	MET →	-1.264	-0.196	.001	.004	3	2
LUAD	ZNHIT1 →	-0.472	-0.207	<.001	<.001	3	2
LUAD	LIMK1 →	-0.583	-0.198	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,178 associations by consensus.

RYBP vs VRK1 — LUAD

Explore this scatter interactively →