RYBP

Across TCGA cell cohorts, RYBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,348 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RYBP-associated GO terms across cancer lineages are Heterochromatin formation, Endosomal transport, and Heterochromatin organization. Each is linked with RYBP in more than 13 cancer types. Because this analysis shows association rather than direction, both RYBP-to-partner and partner-to-RYBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by RYBP-low versus RYBP-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RYBP→partner) and Y-score (partner→RYBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Heterochromatin formation →	+0.077	+1.131	.005	<.001	3	14
SKIN	Endosomal transport →	+0.059	+0.725	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.067	+0.760	<.001	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.060	+0.768	<.001	<.001	3	13
PANCREAS	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.057	+0.511	.001	.006	3	13
STOMACH	Piecemeal microautophagy of the nucleus →	+0.065	+0.927	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,348 associations by consensus.

Heterochromatin formation by RYBP expression — STOMACH

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