RXYLT1

Across TCGA cell cohorts, RXYLT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,172 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RXYLT1-associated GO terms across cancer lineages are rRNA 5'-end processing, Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Protein localization to cilium. Each is linked with RXYLT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RXYLT1-to-partner and partner-to-RXYLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA 5'-end processing grouped by RXYLT1-low versus RXYLT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RXYLT1→partner) and Y-score (partner→RXYLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	rRNA 5'-end processing →	+0.112	+0.551	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.112	+0.551	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein localization to cilium →	+0.051	+0.778	.002	.002	3	10
OESOPHAGUS	Centrosome cycle →	+0.098	+0.906	.005	.006	3	10
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.118	+0.888	.002	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.046	+0.403	.003	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,172 associations by consensus.

rRNA 5'-end processing by RXYLT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →