RXRG

Across TCGA patient cohorts, RXRG protein abundance is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RXRG-associated genes across cancer lineages are F9, KCNK4, and BPIFA1. Each is linked with RXRG in more than 1 cancer types. Because this analysis shows association rather than direction, both RXRG-to-partner and partner-to-RXRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RXRG versus F9 in GBM, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRG→partner) and Y-score (partner→RXRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	F9 →	+0.066	+1.643	.005	.007	3	1
GBM	KCNK4 →	-0.265	-0.616	<.001	.003	3	1
GBM	BPIFA1 →	+0.333	+1.643	.008	.007	3	1
GBM	AKR1C4 →	+0.140	+2.336	.002	.001	3	1
GBM	MXRA7P1 →	+1.095	+2.289	.005	.002	3	1
GBM	UBE2FP3 →	-0.749	-0.763	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

RXRG vs F9 — GBM

Explore this scatter interactively →