Across TCGA pan-cancer cohorts, RXRB mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RXRB data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RXRB mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RXRB expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where RXRB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.686	0.978	.042	4	view →
LSCC	DFS	Quartile	II,III,IV	0.831	0.310	.024	3	view →
PDAC	DFS	Quartile	III,IV	0.307	0.715	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RXRB tumor-vs-normal RNA expression · all RXRB data types