Across TCGA patient cohorts, RXRB protein abundance is significantly associated with the RNA expression of many other genes, with 12,437 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RXRB-associated genes across cancer lineages are FANCE, ZSCAN16, and ZBTB9. Each is linked with RXRB in more than 6 cancer types. Because this analysis shows association rather than direction, both RXRB-to-partner and partner-to-RXRB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRB→partner) and Y-score (partner→RXRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FANCE →	+0.833	+0.330	<.001	<.001	3	7
HNSC	ZSCAN16 →	+0.768	+0.231	<.001	<.001	3	7
LSCC	ZBTB9 →	+0.570	+0.359	<.001	<.001	3	7
LSCC	USP49 →	+0.599	+0.275	<.001	<.001	3	6
HNSC	MCM3 →	+1.010	+0.302	.004	<.001	3	6
OV	NUP153 →	+0.714	+0.280	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,437 associations by consensus.

Exploration

RXRB survival (RNA) · tumor vs normal (RNA) · all RXRB data types