Across TCGA patient cohorts, RXRA protein abundance is significantly associated with the RNA expression of many other genes, with 8,480 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RXRA-associated genes across cancer lineages are FUBP3, RABGAP1, and FBXW2. Each is linked with RXRA in more than 4 cancer types. Because this analysis shows association rather than direction, both RXRA-to-partner and partner-to-RXRA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRA→partner) and Y-score (partner→RXRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FUBP3 →	+0.441	+0.271	<.001	<.001	3	5
HNSC	RABGAP1 →	+0.458	+0.307	.001	.001	3	5
BRCA	FBXW2 →	+0.658	+0.387	<.001	<.001	3	5
BRCA	GAPVD1 →	+0.493	+0.288	<.001	<.001	3	5
LUAD	BHLHA15 →	-1.182	-0.275	<.001	<.001	3	5
BRCA	TSTD2 →	+0.738	+0.341	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,480 associations by consensus.

Exploration

RXRA survival (RNA) · tumor vs normal (RNA) · all RXRA data types