Across TCGA patient cohorts, RXRA mutation is significantly associated with the RNA expression of many other genes, with 3,641 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RXRA-associated genes across cancer lineages are FAXDC2, ELOVL6, and RNU6-39P. Each is linked with RXRA in more than 2 cancer types. Because this analysis shows association rather than direction, both RXRA-to-partner and partner-to-RXRA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRA→partner) and Y-score (partner→RXRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAXDC2 →	-0.462	-2.392	.006	<.001	3	3
BLCA	ELOVL6 →	+0.814	+1.787	<.001	.008	3	3
LUSC	RNU6-39P →	+0.471	+4.099	<.001	.001	3	3
CESC	LINC01072 →	+0.188	+5.345	<.001	.001	3	2
CESC	MIR3667 →	+0.536	+5.196	<.001	.001	3	2
COAD	UBE2F →	+0.336	+3.220	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,641 associations by consensus.

Exploration

RXRA survival (RNA) · tumor vs normal (RNA) · all RXRA data types