Across TCGA cell cohorts, RXRA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,867 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RXRA-associated GO terms across cancer lineages are Positive regulation of vitamin D receptor signaling pathway, Retinoic acid receptor signaling pathway, and Protein destabilization. Each is linked with RXRA in more than 14 cancer types. Because this analysis shows association rather than direction, both RXRA-to-partner and partner-to-RXRA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRA→partner) and Y-score (partner→RXRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of vitamin D receptor signaling pathway →	+0.260	+1.727	.005	<.001	3	15
URINARY_TRACT	Retinoic acid receptor signaling pathway →	+0.137	+1.943	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.094	+0.972	.002	.002	3	13
URINARY_TRACT	Regulation of miRNA metabolic process →	+0.084	+1.299	.004	.002	3	13
BONE	Schwann cell development →	+0.111	+1.138	<.001	<.001	3	13
STOMACH	Negative regulation of protein-containing complex assembly →	+0.089	+1.595	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,867 associations by consensus.

Exploration

RXRA survival (RNA) · tumor vs normal (RNA) · all RXRA data types