RWDD4P2

Across TCGA patient cohorts, RWDD4P2 mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible RWDD4P2-associated genes across cancer lineages are SLC20A1P3, LINC01628, and TXNL4AP1. Each is linked with RWDD4P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RWDD4P2-to-partner and partner-to-RWDD4P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P3 grouped by RWDD4P2-low versus RWDD4P2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD4P2→partner) and Y-score (partner→RWDD4P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC20A1P3 →	+0.125	+6.917	<.001	<.001	3	2
BRCA	LINC01628 →	+0.103	+8.055	<.001	.007	3	2
BLCA	TXNL4AP1 →	+0.178	+5.251	<.001	.006	3	2
BLCA	TRBVB →	+0.143	+6.814	<.001	<.001	3	2
SKCM	DLGAP5P1 →	+0.089	+7.816	<.001	.008	3	1
UCEC	RNA5SP414 →	+1.184	+3.670	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

SLC20A1P3 by RWDD4P2 expression — COAD

Explore this box plot interactively →