RWDD3

Across TCGA patient cohorts, RWDD3 mutation is significantly associated with the RNA expression of many other genes, with 703 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RWDD3-associated genes across cancer lineages are MTCYBP45, RNU6-618P, and RNU6-934P. Each is linked with RWDD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both RWDD3-to-partner and partner-to-RWDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCYBP45 grouped by RWDD3-low versus RWDD3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD3→partner) and Y-score (partner→RWDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTCYBP45 →	+0.171	+4.934	<.001	.002	3	3
HNSC	RNU6-618P →	+0.411	+5.015	<.001	.009	3	2
HNSC	RNU6-934P →	+0.569	+5.736	<.001	.003	3	2
HNSC	SNORA36C →	+0.350	+6.111	<.001	.002	3	2
HNSC	RNA5SP212 →	+0.399	+5.435	<.001	.005	3	2
UCEC	RNA5SP88 →	+0.473	+3.186	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 703 associations by consensus.

MTCYBP45 by RWDD3 expression — CESC

Explore this box plot interactively →