RWDD3

Across TCGA cell cohorts, RWDD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RWDD3-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Positive regulation of mitochondrial ATP synthesis coupled electron transport, and Regulation of DNA damage checkpoint. Each is linked with RWDD3 in more than 10 cancer types. Because this analysis shows association rather than direction, both RWDD3-to-partner and partner-to-RWDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by RWDD3-low versus RWDD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD3→partner) and Y-score (partner→RWDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Zinc ion import into Golgi lumen →	+0.100	+0.606	<.001	.005	3	11
BLOOD_Lymphoma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.073	+0.585	.002	<.001	3	10
BLOOD_Lymphoma	Regulation of DNA damage checkpoint →	+0.080	+0.658	<.001	<.001	3	9
LUNG_SCLC	UDP-galactose transmembrane transport →	+0.164	+1.261	<.001	<.001	3	9
BREAST	Regulation of G2/M transition of mitotic cell cycle →	+0.065	+0.624	<.001	<.001	3	8
STOMACH	Positive regulation of protein K48-linked ubiquitination →	+0.138	+0.786	.003	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,127 associations by consensus.

Zinc ion import into Golgi lumen by RWDD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →