RWDD3

Across TCGA cell cohorts, RWDD3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RWDD3-associated genes across cancer lineages are SLC15A5, C1orf68, and OR4A47. Each is linked with RWDD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RWDD3-to-partner and partner-to-RWDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by RWDD3-low versus RWDD3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD3→partner) and Y-score (partner→RWDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	C1orf68 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR4A47 →	+0.022	+5.022	<.001	.002	3	1
LARGE_INTESTINE	LCE1F →	+0.106	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SLC15A5 by RWDD3 expression — LARGE_INTESTINE

Explore this box plot interactively →