RWDD2B

Across TCGA patient cohorts, RWDD2B mutation is significantly associated with the RNA expression of many other genes, with 523 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RWDD2B-associated genes across cancer lineages are SURF6P1, RN7SL820P, and RNASE9. Each is linked with RWDD2B in more than 2 cancer types. Because this analysis shows association rather than direction, both RWDD2B-to-partner and partner-to-RWDD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SURF6P1 grouped by RWDD2B-low versus RWDD2B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD2B→partner) and Y-score (partner→RWDD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SURF6P1 →	+0.062	+4.685	<.001	.007	3	3
UCEC	RN7SL820P →	+0.176	+2.661	<.001	.006	3	2
COAD	RNASE9 →	+0.119	+4.271	<.001	.003	3	2
HNSC	OR1L1 →	+0.040	+6.008	<.001	.002	3	2
LUAD	OR1E3 →	+0.085	+5.554	<.001	.004	3	2
LUAD	OR10A5 →	+0.434	+5.099	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

SURF6P1 by RWDD2B expression — BLCA

Explore this box plot interactively →