RWDD2B

Across TCGA cell cohorts, RWDD2B mutation is significantly associated with the mutation status of many other genes, with 286 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RWDD2B-associated genes across cancer lineages are SLC9A6, CHADL, and ZC3H12B. Each is linked with RWDD2B in more than 2 cancer types. Because this analysis shows association rather than direction, both RWDD2B-to-partner and partner-to-RWDD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC9A6 grouped by RWDD2B-low versus RWDD2B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD2B→partner) and Y-score (partner→RWDD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC9A6 →	+3.744	+4.044	.003	.003	1	3
LARGE_INTESTINE	CHADL →	+4.329	+4.329	.001	.001	1	2
LARGE_INTESTINE	ZC3H12B →	+2.422	+4.050	.004	.004	1	2
LARGE_INTESTINE	BPNT2 →	+3.007	+3.584	.008	.008	1	2
LARGE_INTESTINE	RARS1 →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	MECR →	+3.007	+3.584	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

SLC9A6 by RWDD2B expression — LARGE_INTESTINE

Explore this box plot interactively →