Across TCGA patient cohorts, RUSC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,470 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RUSC2-associated proteins across cancer lineages are CNN3, MSRB3, and PDLIM7. Each is linked with RUSC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both RUSC2-to-partner and partner-to-RUSC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC2→partner) and Y-score (partner→RUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CNN3 →	+0.722	+0.994	<.001	.001	3	8
BRCA	MSRB3 →	+0.821	+0.730	<.001	<.001	3	7
OV	PDLIM7 →	+0.724	+1.189	<.001	<.001	3	7
GBM	CDH13 →	+0.639	+0.428	<.001	<.001	3	7
OV	TLN1 →	+0.360	+0.970	<.001	.001	3	7
OV	PCOLCE →	+0.964	+1.296	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,470 associations by consensus.

Exploration

RUSC2 survival (RNA) · tumor vs normal (RNA) · all RUSC2 data types