Across TCGA patient cohorts, RUSC2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,625 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RUSC2-associated genes across cancer lineages are CTLA4, CD3D, and LCK. Each is linked with RUSC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUSC2-to-partner and partner-to-RUSC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC2→partner) and Y-score (partner→RUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTLA4 →	-1.062	-0.593	.001	.008	3	2
HNSC	CD3D →	-1.526	-0.607	.001	<.001	3	2
HNSC	LCK →	-1.205	-0.671	<.001	.001	3	2
HNSC	GZMM →	-0.726	-0.607	.002	<.001	3	2
HNSC	TRBJ2-7 →	-1.619	-0.735	<.001	<.001	3	2
HNSC	TRAV9-2 →	-1.027	-0.661	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,625 associations by consensus.

Exploration

RUSC2 survival (RNA) · tumor vs normal (RNA) · all RUSC2 data types