Across TCGA patient cohorts, RUSC2 mutation is significantly associated with the RNA expression of many other genes, with 3,851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUSC2-associated genes across cancer lineages are PUSL1, LINC02114, and NOCT. Each is linked with RUSC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RUSC2-to-partner and partner-to-RUSC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC2→partner) and Y-score (partner→RUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PUSL1 →	+0.506	+3.093	.002	<.001	3	4
KIRP	LINC02114 →	+0.064	+5.770	.008	.003	3	3
UCEC	NOCT →	+0.446	+2.258	<.001	<.001	3	3
UCEC	PANK4 →	+0.343	+2.254	<.001	<.001	3	3
UCEC	ZMYND19 →	+0.402	+1.617	<.001	<.001	3	3
UCEC	KIR3DL1 →	+0.110	+1.495	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,851 associations by consensus.

Exploration

RUSC2 survival (RNA) · tumor vs normal (RNA) · all RUSC2 data types