Across TCGA cell cohorts, RUSC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,998 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RUSC2-associated GO terms across cancer lineages are Regulation of cell-substrate junction organization, Positive regulation of cell-substrate junction organization, and Positive regulation of actin filament bundle assembly. Each is linked with RUSC2 in more than 15 cancer types. Because this analysis shows association rather than direction, both RUSC2-to-partner and partner-to-RUSC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC2→partner) and Y-score (partner→RUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate junction organization →	+0.128	+0.934	<.001	<.001	3	16
BONE	Positive regulation of cell-substrate junction organization →	+0.156	+0.893	<.001	<.001	3	16
BONE	Positive regulation of actin filament bundle assembly →	+0.167	+0.821	<.001	<.001	3	16
BONE	Positive regulation of stress fiber assembly →	+0.159	+0.906	<.001	<.001	3	16
BONE	Positive regulation of focal adhesion assembly →	+0.167	+0.843	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.103	+1.770	.009	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,998 associations by consensus.

Exploration

RUSC2 survival (RNA) · tumor vs normal (RNA) · all RUSC2 data types